What is the difference between medical grade skincare and products I can buy in a high street store? Simply put: The concentrations of ingredients are higher, therefore more active and have to be at higher concentrations and be evidenced to work and do what they say - which is why some products - such as Tretanoin and Azelaic Acid are prescription only. Over the counter products may contain traces of active ingredients but they are not at a level or concentration that will give you real results or the treat skin concerns effectively
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