iS Clinical

iS Clinical - Youth Radiance Collection

If your skin feels like it needs more than your current moisturiser is offering, and the area around your eyes is starting to show tiredness or fine lines that won't shift, this collection is worth a closer look. The iS Clinical Youth Radiance Collection brings together two of the brand's most established products, the Youth Intensive Crème and the Youth Eye Complex, in a single set designed to address hydration, firmness, and the visible signs of ageing across both the face and the delicate eye area.

  • May suit those with dry, mature, or dehydrated skin looking for more targeted anti-ageing support
  • Designed to improve the appearance of fine lines, wrinkles, and loss of firmness over time
  • Provides both immediate hydration and longer-term benefits with continued use
  • Includes a dedicated eye treatment for puffiness, dark circles, and crow's feet
  • Offers a saving compared to purchasing the two products individually


Price: £280.00
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What Is It?

The iS Clinical Youth Radiance Collection is a two-product bundle from iS Clinical, a brand known for clinically formulated skincare used in both professional and consumer settings. The set includes the Youth Intensive Crème (50g) and the Youth Eye Complex (15g), along with a branded cosmetic pouch.

The Youth Intensive Crème is a rich, concentrated moisturiser built around botanically derived hyaluronic acid, peptides, antioxidants, and resurfacing acids. It is designed to provide deep, lasting hydration while working progressively to improve the appearance of skin texture, firmness, and fine lines. It has been clinically tested and is one of the brand's most established products.

The Youth Eye Complex is a targeted treatment for the eye area, formulated with peptides, growth factors, and iS Clinical's proprietary Extremozyme technology. It is designed to address the specific concerns that arise around the eyes, including fine lines, crow's feet, puffiness, and dark circles.

Taken together, the two products form a complementary hydration and anti-ageing routine that covers both the full face and the eye area. The collection is particularly suited to those in their late thirties and above, or anyone whose skin is showing signs of dehydration, fatigue, or premature ageing.

How To Use It

Youth Eye Complex (apply first)

  1. After cleansing, dispense a small amount (approximately half a pump) into the palm of your hand.
  2. Using your ring finger, gently dab and smooth the product around the outer eye area, along the brow bone, and beneath the eye.
  3. Avoid applying too close to the lash line or the inner corners of the eye.
  4. Allow to absorb before applying the crème to the rest of the face.
  5. Use morning and evening.

Youth Intensive Crème (apply second)

  1. Take a small amount and smooth evenly over the face and neck, working over clean skin.
  2. Use morning and evening, or as directed.
  3. For best results, iS Clinical recommends following a complete skincare regimen.
  4. Once opened, the crème is most effective when used within 12 months.

Whats In It?

This is a two-product bundle. The key active ingredients in each product are listed below.

Youth Intensive Crème

The crème does not contain a single hero ingredient. Its effectiveness comes from a layered combination of actives working together.

  • Sodium Hyaluronate and Hyaluronic Acid Microspheres (botanically derived): Two forms of hyaluronic acid that work at different depths in the skin. The standard form draws moisture to the surface; the microsphere form is designed to deliver hydration more deeply over time.
  • Copper Tripeptide-1 (bioidentical): A growth factor that has been clinically shown to support collagen synthesis and assist with skin repair.
  • Superoxide Dismutase (SOD): A naturally occurring enzyme that helps neutralise free radicals, supporting the skin's defence against environmental and UV-related damage.
  • Tetrahexyldecyl Ascorbate (Vitamin C): A stable, oil-soluble form of Vitamin C that provides antioxidant protection and supports a more even, radiant complexion.
  • Retinyl Palmitate: A mild retinoid that contributes to skin renewal and texture refinement. It is gentler than prescription retinoids, which makes the product more accessible for sensitive skin, though it may still cause some initial sensitivity in those who are new to retinoids.
  • Resurfacing acids (including Willow Bark Extract and Sugar Cane Extract): Contribute gentle exfoliation to encourage cell turnover and improve skin texture over time. Note: Willow Bark Extract may not suit very dry or sensitised skin.

Youth Eye Complex

  • Botanically derived Hyaluronic Acid and Microspheres: Hydrate and plump the delicate under-eye area to reduce the sunken appearance associated with dryness and fatigue.
  • Acetyl Octapeptide-3: A peptide associated with temporary muscle-relaxing effects, intended to soften the appearance of expression lines around the eyes and reduce fluid accumulation linked to puffiness.
  • Copper Tripeptide-1 (growth factor): Supports collagen and elastin production in the thin, vulnerable skin around the eye.
  • Pseudoalteromonas Ferment Extract (Extremozyme technology): A marine-derived enzyme complex proprietary to iS Clinical. Clinical data from the manufacturer suggests it supports skin hydration and reduces the depth of wrinkles around the eye area with continued use.
  • Vitamins A, C, and E: Provide antioxidant protection against environmental stressors and free radical damage.

Why We Recommend It

Both products in this collection are well-established within iS Clinical's range and are sold individually as consistent bestsellers. The decision to include them together as a set reflects how well they complement each other in practice: the crème provides broad-spectrum hydration and anti-ageing support across the full face, while the eye complex addresses the more specific and often more stubborn concerns around the eye area that a standard moisturiser is unlikely to resolve.

The formulations are clinically tested and rely on a combination of well-regarded actives, including multiple forms of hyaluronic acid, peptides, and growth factors, rather than a single hero ingredient. This layered approach tends to produce more consistent results across different skin types.

The collection is also reasonably priced relative to the cost of buying both products separately, offering a saving of around 20%.

For those who are already familiar with the brand or looking to move into a more targeted anti-ageing routine, this set offers a practical and coherent starting point.

What To Expect

Both products are designed to deliver noticeable hydration relatively quickly. The crème has a rich, nourishing texture that absorbs without excessive heaviness, and most users report an immediate improvement in how the skin feels. The eye complex is lighter in consistency, which allows it to absorb efficiently around the eye without feeling greasy or interfering with makeup.

Longer-term improvements, including visible reduction in fine lines, improved firmness, and a more even skin tone, typically require consistent use over four to twelve weeks, depending on individual skin conditions.

In a 30-day clinical study on the Youth Eye Complex, the majority of participants reported improvements in skin smoothness and hydration, and a significant proportion saw a reduction in the appearance of dark circles. Results will vary depending on age, skin condition, and how the products are incorporated into a broader routine.

Those with very dry or sensitised skin should approach the Willow Bark Extract in the crème with some caution, and anyone new to retinoids may experience mild adjustment sensitivity during the first few weeks of use. If pregnant or breastfeeding, consult a physician before using either product.

Frequently Asked Questions

Who is this collection most suited to?
The collection is designed primarily for those dealing with the visible signs of ageing, including fine lines, loss of firmness, dehydration, and fatigue around the eyes. iS Clinical states the products are suitable for a range of skin types, including dry, oily, combination, and normal skin. However, those with very sensitised or reactive skin should note that the crème contains Willow Bark Extract and a mild retinoid, both of which can occasionally cause irritation. Patch testing before full use is advisable if your skin is prone to sensitivity.
How soon can I expect to see results?
Hydration benefits from both products are typically noticeable after the first few applications. More significant improvements in fine lines, firmness, and the appearance of dark circles tend to develop over four to twelve weeks of consistent twice-daily use. Results vary by individual, and those with more pronounced concerns may see gradual rather than dramatic change.
Do I need to use both products together, or can I use them separately?
They work independently of each other and can be purchased separately. However, using them together means you are addressing the face and eye area with compatible formulations, which reduces the risk of any conflict between products and supports a more cohesive routine.
Is the Youth Eye Complex suitable for sensitive eyes or contact lens wearers?
The formula is fragrance-free and designed specifically for the delicate skin around the eye. It is generally considered appropriate for sensitive eyes and those who wear contact lenses, provided it is applied correctly (avoiding the lash line and inner corners of the eye). If you experience any irritation, discontinue use and seek advice.
How does the Youth Eye Complex differ from a standard eye cream?
Many eye creams focus primarily on hydration. This formula additionally incorporates Extremozyme technology (a marine-derived enzyme complex), acetyl octapeptide-3 (a muscle-relaxing peptide), and copper tripeptide growth factors, making it a more active treatment. It addresses hydration alongside puffiness, dark circles, collagen support, and expression lines, which is a broader scope than most over-the-counter eye creams in a similar price range.
Is this collection suitable to use during pregnancy or whilst breastfeeding?
iS Clinical recommends consulting a physician before use if you are pregnant, planning to become pregnant, or breastfeeding. This applies to the full range, not just this collection.
How long will the products last?
The Youth Intensive Crème (50g) and the Youth Eye Complex (15g) are typical sizes for twice-daily use. The eye complex is estimated to last around three to four months with standard use. The crème will vary depending on how much is applied, though once opened, iS Clinical recommends using it within 12 months for optimal effectiveness.

Interested in learning more?

Explore the full product details, pricing, and latest information on the official site to decide whether it is right for you.

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