NEOSTRATA® Launches MicroDiPeptide Technology: A New Standard in Skin Rejuvenation

NEOSTRATA®, has launched MicroDiPeptide²²⁹®, a patented peptide technology designed to visibly lift, firm, and sculpt the skin. Developed over eight years, this marks a significant advancement in the brand’s Skin Active range¹.

Enhanced Penetration Through Advanced Peptide Science

MicroDiPeptide²²⁹® is a proprietary dipeptide that is 2.5 times smaller than traditional cosmetic peptides. Its reduced molecular size complies with the 500 Dalton Rule, allowing for significantly deeper penetration into the skin’s surface layers². This structural advantage enables the ingredient to target and activate multiple biological pathways related to skin firmness and resilience.

Biological Pathways Targeted by MicroDiPeptide²²⁹®

Clinical research has demonstrated that MicroDiPeptide²²⁹® enhances the skin’s natural support matrix by stimulating five key skin components³:

• Pro-Collagen: Supports improved skin structure and firmness.

• Elastin: Enhances skin elasticity and resilience.

• Hyaluronic Acid: Promotes moisture retention for hydrated, plump skin.

• Decorin: Regulates collagen formation to improve skin tightness.

• Fibronectin: Strengthens the extracellular matrix for smoother, more even skin texture.

Suitable for Sensitive and Eczema-Prone Skin

MicroDiPeptide²²⁹® has undergone extensive clinical testing and has shown efficacy in improving skin condition in individuals with sensitive and eczema-prone skin. It demonstrated a reduction in visible eczema lesions and improved skin comfort, attributed to its anti-inflammatory properties⁴. Unlike commonly used active ingredients such as retinol, this peptide provides anti-ageing benefits with reduced risk of irritation, making it suitable for a broader range of skin types.

Updated NEOSTRATA® Skin Active Products Featuring MicroDiPeptide²²⁹®

The following formulations in the NEOSTRATA® Skin Active range have been reformulated to incorporate MicroDiPeptide²²⁹®, enhancing their performance in lifting and firming the skin:

• Tri-Therapy Lifting Serum: A lightweight serum that smooths fine lines and supports skin firmness.

• Firming Collagen Booster: Formulated to increase collagen and elastin production, improving skin density and volume.

• Cellular Restoration: Targets visible signs of cellular ageing and supports skin renewal.

• Matrix Support SPF 30: A multi-tasking day cream providing UV protection while rebuilding skin firmness.

• Intensive Eye Therapy: Reduces crow’s feet, puffiness, and dark circles to enhance the eye contour.

Commitment to Scientific Innovation

The introduction of MicroDiPeptide²²⁹® reflects NEOSTRATA’s ongoing dedication to ingredient innovation and clinical skincare. As one of the final research projects led by NEOSTRATA founders Dr. Eugene J. Van Scott and Dr. Ruey J. Yu, the technology represents a continuation of their pioneering contributions to dermatological science⁵.

^References:

1. ^{NEOSTRATA® internal R&D data on peptide development timeline.}

2. ^{Dalton, M. (2005). "The 500 Dalton Rule for Skin Penetration". Journal of Dermatological Science.}

3. ^{NEOSTRATA® clinical efficacy studies, 2024.}

4. ^{Clinical trial data on MicroDiPeptide²²⁹® in eczema-prone patients, NEOSTRATA®, 2023.}

5. ^{Historical records of Dr. Van Scott and Dr. Yu’s contributions to cosmetic dermatology.}