You Cannot Rebuild the Skin Without the Materials to Build It
Introducing Celora™ Vita: a biorestorative injectable that addresses skin ageing at its source
Much of what we understand as skin ageing is not simply the passage of time. It is the progressive depletion of the raw materials the dermis needs to maintain itself, the amino acid substrates that fibroblasts rely on to synthesise collagen, elastin and the extracellular matrix.
When those substrates run low, the skin’s ability to repair and renew becomes limited, and no amount of volumisation addresses that underlying deficit. Celora™ Vita has been developed to replenish what is missing at a biological level. With this launch, DermaFocus marks its next strategic step, evolving from a trusted distributor into a brand owner and leader in regenerative aesthetics.
Celora™ Vita: a biorestorative injectable approach
Celora™ Vita is an injectable formulation medical device intended for intradermal administration to support full facial skin biorestoration and overall skin quality improvement.
The formulation combines:
- A targeted combination of amino acids, chosen for their involvement in collagen synthesis, elastin production and complete extracellular matrix renewal
- Low molecular weight hyaluronic acid, selected for its role in dermal hydration and microenvironment support.[AS1.1] ¹
This composition reflects a deliberate move away from volumisation and towards substrate-based skin biorestoration, supplying the dermis with the essential building blocks behind skin quality.
The scientific rationale
Skin quality depends on active fibroblasts maintaining collagen, elastin and hyaluronic acid within the extracellular matrix. With age and biological stress, this process slows as fibroblast efficiency declines.2
Amino acids are essential substrates for structural skin proteins. As collagen and elastin production decreases from early adulthood, reduced amino-acid availability limits protein synthesis. This contributes to loss of elasticity, hydration and dermal support.3,4
The amino acids in Celora™ Vita have each been selected because they play a precise and complementary role in complete extracellular matrix renewal. Glycine, proline, lysine and alanine serve as fundamental structural building blocks of collagen and elastin. The full set of branched-chain amino acids, valine, leucine and isoleucine, support protein synthesis and tissue repair. Serine and alanine contribute to the natural moisturising factor (NMF), enhancing dermal hydration, while cysteine and glycine support antioxidant defence through the glutathione pathway, helping protect the skin against oxidative stress.5
Celora™ Vita is one of the most complete amino acid blends in its class and is designed for physiological regeneration, supporting long-term skin quality and durability.
Clinical integration and patient selection
Clinical evidence supports measurable improvements across key skin quality parameters, including hydration5,6 natural brightness6,1 firmness and elasticity1 skin texture,6 and wrinkles and fine lines6,1 for comprehensive skin quality improvement. In a 2024 study by Scarano et al., significant improvements vascularity and collagen type 3 synthesis were observed following a structured amino acid treatment protocol, with results maintained at follow-up.
Celora™ Vita has been developed to integrate seamlessly into modern aesthetic practice. Its versatility allows it to be incorporated across a wide range of indications and treatment plans, including:
• Early intervention and prejuvenation protocols
• Skin quality optimisation in patients with early to moderate signs of ageing1
Positioning within the DermaFocus regenerative portfolio
Celora™ Vita sits alongside Plinest® and Purasomes within the DermaFocus regenerative portfolio. For practitioners building regenerative protocols, this offers the ability to address multiple sources of skin ageing within a single structured programme. For DermaFocus, it marks a shift from distribution partner to active participant in the innovation, education and clinical development of regenerative aesthetics.
Milad Bemana, executive director, shares, “Regenerative aesthetics is moving in a clear direction practitioners want treatments that restore skin quality, not just alter appearance. Celora™ Vita reflects that direction. It gives clinicians a scientifically grounded tool to address substrate deficiency something that has been overlooked for too long and it does so within a framework that integrates naturally with the protocols they are already building.”
Acknowledgements: DermaFocus thanks Dr Raquel Amado, Mr George Christopoulos, Dr Jordan Faulkner, Dr Xavier Goodarzian, Dr Steven Land, Dr Kam Lally, Dr Yusra Al-Mukhtar, Dr Olivia McCabe-Robinson and Dr Sach Mohan for their clinical expertise and input during the development of Celora™ Vita[AS3.1].
For Celora™ Vita[AS4.1] training and product information got to Celora™ Vita - DermaFocus
References:
1. Scarano A et al., 2024. J Ultrasound.
2. Shin SH et al., 2023. Front Physiol.
3. Noguchi A et al., 2009. Nutritional Cosmetics: Beauty from Within.
4. Solano F. 2020. Adv Exp Med Biol.
5. Scarano A et al., 2024. Eur J Musculoskel Dis.
6. Svolacchia F et al., 2023. Eur Rev Med Pharmacol Sci.