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Cryoneuromodulation or Focused Cold Therapy™ is a minimally invasive procedure and so it is suitable for most people in general good health and with reasonable expectations of the outcome of the procedure.
It may not be as effective at treating very deep wrinkles or even very fine wrinkles. A trained practitioner will be able to tell you whether you are a good candidate for this type of procedure or whether you would benefit from another treatment option or a combination of treatment types.
There are reported cases of non-responders where cryoneuromodulation simply doesn’t deactivate nerves successfully enough to relax the muscles which cause the wrinkles.