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Mesotherapy is a medical technique first devised in the 1950s by a Frenchman called Dr Michel Pistor. It involves the micro-injection of a specially prepared mixture of vitamins, amino acids, and medications, placed into the mesoderm (i.e. just millimetres under the skin) within a problematic area. It was initially used to treat such conditions as rheumatism, sports injuries, and for the improvement of blood circulation, and has now been used successfully by some practitioners for the treatment of cosmetic conditions, including skin rejuvenation, hair re-growth, localised fat reduction, and as a treatment for cellulite. It still maintains its roots in France where it is commonly practiced by more than 15,000 practitioners and is taught in French medical schools. Mesotherapy is now also gaining widespread acceptance by cosmetic clinics in the UK and the USA. Many people are not comfortable with the concept of multiple injections, so aesthetic device manufacturers have sought ways to offer no-needle alternatives. If you are considering treatment with no-needle mesotherapy, the following information will give you a basic understanding of the procedure. It can't answer all your questions, since a lot depends on the individual patient. Please ask a practitioner about anything you don't understand.