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In Men – The procedure is considered comfortable with a mild pinching or pressure sensation during treatment. There are generally no side effects from PRP treatment injected into the penis, but you can expect the effects of the numbing cream to last for 30 – 60 minutes after treatment, at which point you may notice mild soreness which can last for 24 hours or so. There may be redness or mild bleeding at the points of injection. In Women – Again, the procedure is regarded as comfortable due to the application of the local anaesthetic cream, often meaning that a sensation of pressure is all that is felt. Side effects are again few but may include soreness after the anaesthetic wears off and bleeding or spotting from the injected areas for a day.When PRP is used for sexual rejuvenation it does involve injecting intimate areas of the body and therefore carries a risk of infection, bleeding, bruising and less commonly nerve damage.