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“Polynucleotides are fillers.” Polynucleotides are not dermal fillers. They do not add volume, contour the face or change facial structure. Instead, they work by supporting skin regeneration and improving tissue quality over time.
“They’re new and untested.” Polynucleotides have been used in medical and regenerative settings for decades. Their application in aesthetic medicine builds on an established scientific and clinical foundation.
 “They’re made from human DNA.” Aesthetic polynucleotides are derived from purified fish DNA, typically salmon or trout bred for human consumption. Advanced purification processes remove proteins and impurities, resulting in a biocompatible product suitable for injectable use.
“They work instantly.” Polynucleotides are designed to deliver gradual improvement, not immediate cosmetic change. Results develop over weeks and continue to improve as collagen and elastin production is supported.
“They’re unsafe for delicate areas.” When delivered by a trained medical professional using appropriately regulated products, polynucleotides are widely used in delicate areas such as the under-eye region and neck due to their non-volumising nature.
Understanding what polynucleotides can – and cannot – do helps set realistic expectations, deliver safe results and ensure treatments are chosen for the right reasons.

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