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<h3><img border="1" hspace="9" alt="Zyderm and Zyplast Packs" align="right" src="https://www.consultingroom.com/uploads/Image_Directory/Product/zyderm_zyplast_pack.jpg" />Product Summary</h3>
<p>Zyderm® and Zyplast® implants, introduced in the early 1980s, remain the most widely used, safe, and effective choices for smoothing lines, wrinkles, scars, and for defining the lip border. </p>
<p>More than 1 million treatments in over 40 countries have been administered with Zyderm® and Zyplast® implants.</p>
<p><span style="background: rgb(255, 255, 255);">From 2011 this product is no longer generally available in the U.K. as use declined due to the introduction of newer fillers that do not require a patch test prior to treatment</span><span style="background: rgb(255, 255, 255);">.</span><br /></p>
<h3>Generic name</h3>
<p>Bovine dermal collagen plus 0.3% lignocaine.</p><br />
<h3>How is it made?</h3>
<p>From cow skins.</p><br />
<h3>Is a skin test required before treatment? </h3>
<p>Yes. Four weeks prior to the procedure, Collagen Test Implant is administered intradermally into the volar forearm to determine if a patient has a sensitivity to the implants. Ninety-seven percent (97%) of men and women tested can be treated with Zyderm® and Zyplast® implants.</p><br />
<h3>Is it temporary or permanent? </h3>
<p>Collagen is completely broken down within the skin over a period of months, eventually leaving no trace of the filler. </p><br />
<h3>Licenced status</h3>
<p>Medical device.</p><br />
<h3>Should be used by </h3>
<p>Trained members of the medical profession only.</p><br />
<h3>Product range </h3>
<p><strong>Zyderm® 1 implant</strong> 
<p>Is used to treat fine lines, wrinkles, shallow scars and thin-skinned areas. </p><strong>Zyderm® 2 implant</strong> 
<p>Is used to treat moderate lines, wrinkles and scars. Both are administered by an injection with a fine-gauge needle just beneath the surface of the skin. <br /></p><strong>Zyplast®</strong> 
<p>Is a form of injectable collagen that is cross-linked with the chemical glutaraldehyde to strengthen the collagen fibres. It is used to treat pronounced scars, lines, and furrows, as well as to define the lip border.</p><br />
<h3>Not to be used in</h3>
<p>Patients who have a reaction to the required skin test, or previous allergic reaction to injectable collagen products or lidocaine, or patients who have a history of serious allergic (anaphylactic) reactions, Zyderm® or Zyplast® Collagen must not be used. Also, if you are undergoing or planning to undergo desensitization injections to meat products, you cannot receive injectable collagen.</p>
<p>Individuals with a known hypersensitivity to lignocaine.</p>
<p>Pregnant or breastfeeding women.</p>
<p>Individuals with a history of autoimmune disease.</p>
<p>Patients who have a tendency to develop hypertrophic scars.</p><br />
<h3>Duration of effect </h3>
<p>This depends upon the degree of correction required, your age and lifestyle as well as the correct placement of the product by a practitioner.</p><br />
<h3>Reported side effects </h3>
<p>Transient erythema (redness), swelling, pain, itching, discoloration or tenderness at the implant site. Occasionally, injected collagen has been reported as visible in the skin, in the form of a small raised or white area at the treatment site, which may persist from a few weeks to several months. Some areas (such as compressed scars) resist precise placement of the material, resulting in a slight elevation beside the defect.</p>
<p>With more than 1 million people treated since 1976, injectable collagen has proven to be safe. However, a small number (one to two percent) have developed an allergic reaction after one or more injections, which has consisted of prolonged redness, swelling, itching and/or firmness at some or all of the sites. On rare occasions, these reactions can proceed to a cyst-like reaction that can drain, and may form a scar. Between one and nine months is the usual duration, but a few cases have involved intermittent flare-ups which have exceeded 24 months. </p>
<p>Importantly, many people who developed an allergic reaction after treatment did not report or recognize a response to the skin test. (With proper monitoring of the skin test, many of these later reactions could have been prevented.)</p><br />
<h3>Costs</h3>
<p>Again, this depends on area treated and how much is required, and the practitioner doing the treatment, but ranges are in the region of: £100 - £400</p><br />
<h3>Clinical results</h3>
<p>Rigorous clinical trials to determine the safety and efficacy of Zyderm® and Zyplast® collagen implants were conducted from 1976 to 1981. This data was submitted to the Food and Drug Administration (FDA) and Zyderm® and Zyplast® implants were cleared for marketing in 1981 and 1985 respectively. No other injectable collagen implants currently on the market have undergone such extensive study.</p>

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