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As the prevalence of obesity increases, more and more drugs that assist with weight loss are being developed. Initial approaches in developing weight loss drugs were focused on increasing energy expenditure.
Later, as other endocrine or hormone-mediated mechanisms for weight gain were unearthed, drugs targeting newly discovered receptors and/or enzymes that help with appetite control, with improved efficacy, tolerability and safety, were introduced.
These have become the mainstay of medical weight loss treatments and have revolutionised the approach to weight loss for millions of people who have struggled for years.
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