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The appearance of a pustular/papular rash associated with high levels of Vitamin B12 is well described in the medical literature even though the exact mechanism appears to be unknown.
Vitamin B12 is a water-soluble vitamin that must be ingested daily and absorbed effectively by the digestive tract in order to maintain optimal health.
Most people get enough vitamin B12 by eating a variety of foods. Those that naturally contain vitamin B12 include lean red meats, poultry, fish, brewer’s yeast, and dairy products, such as milk, cheese, and yogurt.
Vitamin B12 is also added to some breakfast cereals, breads, and other fortified food products.