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The main difference between the two is the potency. STS is about twice as potent as polidocanol.
Potency refers to the concentration of the sclerosing agent needed to achieve the desired effect. STS is about twice as potent as polidocanol, meaning a lower concentration of STS is needed to be effective. This can be beneficial as it means there is less risk of damaging the surrounding tissue.
It is important to use the appropriate concentration according to the size of the vein being treated.
The concentration of the sclerosing agent used will vary depending on the size of the vein being treated. For smaller veins, a lower sclerosing agent concentration will be used. For larger veins, a higher concentration may be required.