Edit Does stress age me?

<p><strong>Does Stress Age Me?</strong></p> <p>“Stress can cause detrimental physiological and functional consequences in the skin. Skin ageing is characterised by the formation of <a title="lines and wrinkles" href="/conditions/lines-and-wrinkles/" target="_blank" rel="noopener">lines and wrinkles</a>, increased <a title="pigmentation" href="/conditions/pigmentation" target="_blank" rel="noopener">pigmentation</a>, loss of elasticity and firmness, and dull skin; this can be caused by both intrinsic and extrinsic factors. While the exact mechanism of how stress impacts skin ageing is still being studied, we do know that epinephrine, norepinephrine and cortisol increase DNA damage, interfere with DNA repair, and alter transcriptional regulation of the cell cycle.</p> <p>UV irradiation, smoking and air pollution have been confirmed as critical chronic stressors that impact skin ageing significantly. Telomere shortening has emerged as another possible cellular mechanism linking chronic psychological stress and ageing. Various chronic stress situations have been associated with shorter telomere length, including caregiving for a family member with chronic conditions or elderly dementia patients, major depression, childhood adversity, and exposure to intimate partner violence. Recent studies have also shown the negative effect of sleep deprivation on skin ageing. Lack of sleep creates increased signs of intrinsic skin ageing like fine lines, uneven pigmentation and reduced elasticity. Skin also recovers more slowly after skin barrier disruption.”</p>

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