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<div class="pdf-text-layer color-660be6">A Brief History Of Botulinum Toxin Injections Botulinum toxin is a purified substance, which is derived from bacteria and injected into muscles to block nerve signals. The active ingredient of wrinkle-relaxing injections, this molecule is used for softening <a title="Wrinkles" href="/conditions/Lines-and-Wrinkles" target="_blank" rel="noopener">fine lines and wrinkles</a>, as well as stopping <a title="Hyperhidrosis" href="/conditions/hyperhidrosis-excessive-sweating" target="_blank" rel="noopener">excessive sweating (</a><a title="Hyperhidrosis" href="/conditions/hyperhidrosis-excessive-sweating" target="_blank" rel="noopener">hyperhidrosis</a><a title="Hyperhidrosis" href="/conditions/hyperhidrosis-excessive-sweating" target="_blank" rel="noopener">)</a>, but this has only occurred in recent decades.</div>
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<div class="pdf-text-layer color-660be6">In 1987, a Canadian ophthalmologist from Vancouver, called Jean Carruthers, started using botulinum toxin to help her patients control their eye spasms. Coincidentally, these patients then realised that their frown lines had reduced, too! It was then that Jean suspected that she had stumbled upon a new treatment method. To further test this theory, she injected herself with the same botulinum toxin solution, which confirmed her suspicions.</div>

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