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The recommended reconstituted dose of Botox is 155-195 units, administered intramuscularly as 0.1 ml (5 units) injections to between 31 and 39 sites around the head and back of the neck. The recommended re-treatment schedule is every 12 weeks.
As it turns out many patients were very glad that NICE had recommended this treatment as a cost effective use of NHS resources because it could literally turn their life around. However, despite the NICE recommendations being published in June, NHS settings in England and Wales had until September to allocate funding for it, and for many this was too long to wait and continue with their ‘painful’ situation, especially as it was unclear just how easy it would be to get NHS treatment even when funds were allocated by each PCT.