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The timing of the onset of acne in adolescence makes clear the link to hormones, and sex hormones have significant and direct effects on the skin.
The fact that the incidence of acne falls more quickly with advancing age in men than in women is almost certainly due to hormonal differences.
The male hormone environment is pretty stable and constant in comparison with women, whose hormones fluctuate with their menstrual cycle which can contribute to flare-ups in the condition.